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发布日期:2023-02-22
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王群 教授



  王群,19688月生。于华东师范大学获得学士,硕士及博士学位。1990年至20232月在华东师范大学生命学学院先后担任助教,讲师,副教授和教授,20233月至今于js6668金沙登录入口担任教授、博士生导师。主持包括国家自然科学基金(6项)、上海市曙光学者、上海市教委创新重点和上海市科委基础重点在内的项目。已发表论文160余篇,其中SCI收录100余篇,以团队负责人在J Biol ChemJ ImmunolFASEBFront ImmunolEnviron PollutFish Shellfish ImmunolDev Comp ImmunolMol Immunol生物学二区Top、医学二区Top、环境类二区Top、农林科学一区Top、动物学1区等SCI期刊发表论文90余篇。曾获上海市曙光学者(2008)、明治生命科学奖(2011)、申银万国奖(2006)、国家科学技术进步奖(20106/10)和上海市科学技术进步奖(20053/12)。

 

教育与工作背景

教育经历:

19869-19906月,华东师范大学,生物系,本科

19939-19967月,华东师范大学,生物系,硕士研究生

19989-20027月,华东师范大学,生命科学学院,博士研究生

工作经历:

19907-19956月,华东师范大学,生物系,助教

19957-20006月,华东师范大学,生物系,讲师

20007-200512月,华东师范大学,生命科学学院,副教授

200512-20232月,华东师范大学,生命科学学院,教授

20233-至今,js6668金沙登录入口,js6668金沙登录入口,教授

20045-20056月,美国Auburn University,访问学者

 

主要研究方向

甲壳动物分子生物学

研究兴趣:

1.甲壳动物生殖生物学

2.甲壳动物分子免疫学

欢迎生殖生物学、免疫学、蛋白质组学或生物信息学专业的博士到本实验室从事博士后研究工作

 

社会兼职

中国动物学会理事

中国动物学会甲壳动物学分会副理事长

上海市动物学会常务理事

中国水产学会水产动物免疫学委员会委员

 

主持和参与的科教项目

主持国家自然科学基金项目的名称:

1. 中绒螯蟹Hippo信号通路在抗菌免疫中的作用机制研究(31970490

2. FOXL2调控中华绒螯蟹外源性Vg合成和吸收机制的研究(31672639)

3. 中华绒螯蟹精子膜蛋白组成及其修饰机理的研究(31172393

4. 中华绒螯蟹副性腺相关功能蛋白和基因的研究(30972241

5. 中华绒螯蟹精子发生相关基因的研究及其营养调控(30671607

6. 中华绒螯蟹精子代谢和精子质量评价研究(30300265

上海市科委基础重点项目:

红螯螯虾遗传育种的基础研究连锁图构建(08JC1408300

 

发表的主要论文情况

发表学术论文160余篇,其中SCI论文100余篇,以下为近5年的代表性论文:

[1] Li, J., K. Zhao, H. Li, K. Zhou, Q. Wang, and W. Li. 2022. Immunological functional differentiation of two transmembrane variants of Dscam in Chinese mitten crab. Developmental and Comparative Immunology 128.

[2] Nan, X., X. Jin, Y. Song, K. Zhou, Y. Qin, Q. Wang, and W. Li. 2022. Effect of polystyrene nanoplastics on cell apoptosis, glucose metabolism, and antibacterial immunity of Eriocheir sinensis. Environmental Pollution 311.

[3] Wang, Y., X. Nan, S. Hao, K. Zhao, Y. Guo, Q. Wang, and W. Li. 2022. AKT regulates hemocyte proliferation via glucose metabolism in Eriocheir sinensis. Fish & Shellfish Immunology 127: 247–255.

[4] Zhao, H., Z. Chen, H. Li, Y.-H. Zhao, Q. Wang, and W.-W. Li. 2022. Suppressed COP9 signalosome 5 promotes hemocyte proliferation through Cyclin E in the early G1 phase to defend against bacterial infection in crab. FASEB Journal 36.

[5] Zhao, K., Y. Qin, X. Nan, K. Zhou, Y. Song, W. Li, and Q. Wang. 2022. The role of ficolin as a pattern recognition receptor in antibacterial immunity in Eriocheir sinensis. Fish & Shellfish Immunology 128: 494–504.

[6] Zhou, K., L. Bai, X. Nan, K. Zhao, Y. Song, W. Li, and Q. Wang. 2022. FADD regulates antibacterial immune responses via the immune deficiency signaling pathway in the Chinese mitten crab. Developmental and Comparative Immunology 128.

[7] Zhou, K., Y. Qin, Y. Song, K. Zhao, W. Pan, X. Nan, Y. Wang, Q. Wang, and W. Li. 2022. A novel Ig domain-containing C-Type lectin triggers the intestine-hemocyte axis to regulate antibacterial immunity in crab. Journal of Immunology 208: 2343-2362.

[8] Li, H., X.-K. Jin, K.-M. Zhou, H. Zhao, Y.-H. Zhao, Q. Wang, and W.-W. Li. 2021. Down syndrome cell adhesion molecule triggers membrane-to-nucleus signaling-regulated hemocyte proliferation against bacterial infection in invertebrates. Journal of Immunology 207: 2265–2277.

[9] Li, W., and Q. Wang. 2021. Recent progress in the research of exosomes and Dscam regulated crab antiviral immunity. Developmental and Comparative Immunology 116.

[10] Sun, W., H. Li, Y. Zhao, L. Bai, Y. Qin, Q. Wang, and W. Li. 2021. Distinct vitellogenin domains differentially regulate immunological outcomes in invertebrates. JOURNAL OF BIOLOGICAL CHEMISTRY 296.

[11] Zhao, Y., H. Li, H. Zhao, W.K. Sun, Q. Wang, and W. Li. 2021. An ancient interleukin-16-like molecule regulates hemocyte proliferation via integrin beta 1 in invertebrates. Journal of Biological Chemistry 297.

[12] Bai, L., K. Zhou, H. Li, Y. Qin, Q. Wang, and W. Li. 2020. Bacteria-induced IMD-Relish-AMPs pathway activation in Chinese mitten crab. Fish & Shellfish Immunology 106: 866–875.

[13] Li, Q., H. Zhao, L. He, H. Yang, and Q. Wang. 2020. Leptin is involved in acrosome reaction by facilitating activation of MAPK cascades in the Chinese mitten crab, Eriocheir sinensis. Animal Biology 70: 81–95.

[14] Sun, W., H. Li, Y. Zhao, L. Bai, Y. Qin, Q. Wang, and W. Li. 2020. Distinct vitellogenin domains differentially regulate immunological outcomes in invertebrates. Journal of Biological Chemistry 296: 100060.

[15] Sun, W., L. Li, H. Li, K. Zhou, W. Li, and Q. Wang. 2020. Vitellogenin receptor expression in ovaries controls innate immunity in the Chinese mitten crab (Eriocheir sinensis) by regulating vitellogenin accumulation in the hemolymph. Fish & Shellfish Immunology 107: 480–489.

[16] Tang, B., Z. Wang, Q. Liu, H. Zhang, S. Jiang, X. Li, Z. Wang, Y. Sun, Z. Sha, H. Jiang, X. Wu, Y. Ren, H. Li, F. Xuan, B. Ge, W. Jiang, S. She, H. Sun, Q. Qiu, W. Wang, Q. Wang, G. Qiu, D. Zhang, and Y. Li. 2020. High-quality genome assembly of Eriocheir japonica sinensis reveals its unique genome evolution. Frontiers in Genetics 10.

[17] Tang, M., X. Li, L. Yang, Q. Wang, and W. Li. 2020. A class B scavenger receptor mediates antimicrobial peptide secretion and phagocytosis in Chinese mitten crab (Eriocheir sinensis). Developmental and Comparative Immunology 103.

[18] Jin, X., W. Li, M. Xu, Y. Zhu, Y. Zhou, and Q. Wang. 2019. Transcriptome-wide analysis of immune responses in Eriocheir sinensis hemocytes after challenge with different microbial derivatives. Developmental and Comparative Immunology 101.

[19] Li, D., Z. Wan, X. Li, M. Duan, L. Yang, Z. Ruan, Q. Wang, and W. Li. 2019. Alternatively spliced down syndrome cell adhesion molecule (Dscam) controls innate immunity in crab. Journal of Biological Chemistry 294: 16440–16450.

[20] Qin, X., X. Jin, K. Zhou, H. Li, Q. Wang, W. Li, and Q. Wang. 2019. EsGPCR89 regulates cerebral antimicrobial peptides through hemocytes in Eriocheir sinensis. Fish & Shellfish Immunology 95: 151–162.

[21] Ruan, Z., Z. Wan, L. Yang, W. Li, and Q. Wang. 2019. JAK/STAT signalling regulates antimicrobial activities in Eriocheir sinensis. Fish & Shellfish Immunology 84: 491–501.

[22] Wan, Z.-C., D. Li, X.-J. Li, Y.-T. Zhu, T.-H. Gao, W.-W. Li, and Q. Wang. 2019. B52 promotes alternative splicing of Dscam in Chinese mitten crab, Eriocheir sinensis. Fish & Shellfish Immunology 87: 460–469.

[23] Yang, L., X. Li, X. Qin, Q. Wang, K. Zhou, H. Li, X. Zhang, Q. Wang, and W. Li. 2019. Deleted in azoospermia-associated protein 2 regulates innate immunity by stimulating Hippo signaling in crab. Journal of Biological Chemistry 294: 14704–14716.

[24] Li, X.-J., L. Yang, D. Li, Y.-T. Zhu, Q. Wang, and W.-W. Li. 2018. Pathogen-specific binding soluble Down syndrome cell adhesion molecule (Dscam) regulates phagocytosis via membrane-bound Dscam in crab. Frontiers in Immunology 9.

 

荣誉及奖励

2005年度上海市科技进步一等奖,第三

2005-2006学年华东师范大学人生发展导航优秀教师导师称号

2006年度申银万国奖

2008年度曙光学者

2010年度国家科技进步二等奖,第六

2011年度华东师范大学科研新星

2011年度明治生命科学奖

 

联系方式

通讯地址:上海市浦东新区沪城环路999

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邮编201306

办公地址:js6668金沙登录入口

E-mailqunwang@shou.edu.cn